Parkinson's disease can be difficult to diagnose, as there are Parkinsonian features of other causes or uncertainty in the early stage of Parkinson's disease (PD). Moreover, it is important to note that missed clinical diagnoses or delayed diagnosis rates were reported in 15-20% of the Parkinson's disease in the early stage. 

The purposes of this study were: 1) to compare diagnostic accuracy of 18F FP-CIT PET/CT; 2) to validate of clinical effectiveness of 18F FP-CIT PET/CT in suspicious early Parkinson disease; and 3) to assess the budgetary impact of FP-CIT PET/CT in early use in the diagnosis of Parkinson’s disease.